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1.Select all of the TRUE statements. (Select all that apply.) Steroid hormomes a

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Question

1.Select all of the TRUE statements. (Select all that apply.)

Steroid hormomes are an example of an effector which regulates regulatory transcription factor activity.

RNAi is used in eukaryotic cells only to defend against viruses and transposable elements.

DNA that contains actively transcribed genes would most likely contain chromatin in the closed configuration.

The exons of a gene are always expressed in a functional protein.

Activator proteins bind to enhancer sequences and repressor proteins bind to silencer sequences.

The CpG islands upstream of housekeeping genes are unmethylated.

Nucleosome location may be changed by a process called ATP-dependent chromatin remodeling.

DNA methylation activates gene expression.

2.Select all of the TRUE statements. (Select all that apply.)

a. Constitutive genes are those that have constant levels of expression.

A riboswitch is an RNA molecule that can exist in two different conformations. Conversion from one to another is due to the binding of a small molecule to the riboswitch.

DNA that contains instructions for two or more structural genes produces monocistronic mRNA.

Negative transcriptional regulation is conducted by activator proteins.

In the lac operon, the operator is an example of a trans-effect genetic regulation.

Operons that code for catabolic enzyme systems are typically regulated by repressors.

3. Select all of the TRUE statements. (Select all that apply.)

A mutation in a gene that restores the wild-type phenotype of a second gene is called a suppressor mutation.

The term mutation refers to a heritable change in the genetic material.

Breakpoints in chromosome can lead to mutant phenotypes when they occur in the middle of a gene.

The most common genotype in a population is called the mutant genotype.

Homologous recombination repair requires the presence of a sister chromatid.

The Ames test may be used to determine if an agent is a mutagen.

A mutation in a promoter region that causes the promoter sequence to more closely resemble the consensus sequence is called an up promoter mutation and decreases transcription.

Trinucleotide repeat expansion frequently results in the addition of extra histidine amino acids to the protein.

I. Because the genetic code is degenerate, silent mutations can occur in certain bases within a codon, such as the third base, so the specific amino acid is not changed.

4. Select all of the TRUE statements. (Select all that apply.)

The process of conjugation may introduce new genes into the recipient strain, altering its genotype.

The direct movement of DNA between two bacteria of the same generation is called horizontal genetic transfer.

In conjugation, the strand of DNA that is transferred from the donor cell to the recipient cell is single stranded.

An episome is a segment of bacterial DNA that can exist as a plasmid or be integrated into the bacterial chromosome.

A cell with an F factor integrated into the bacterial chromosome is called F

f. During transformation, homologous recombination may occur if the sequence of the introduced DNA has no similarity to the host DNA.

5. Select all of the TRUE statements. (Select all that apply.)

a. Antibody diversity in the immune system is produced by site-specific recombination.

To date, there are no indications that transposable elements offer a selective advantage to a species.

Recombination between sister chromatids produces new combinations of alleles that may be beneficial to the species.

LINEs and SINEs together constitute over 30% of the human genome.

a.

Steroid hormomes are an example of an effector which regulates regulatory transcription factor activity.

b.

RNAi is used in eukaryotic cells only to defend against viruses and transposable elements.

c.

DNA that contains actively transcribed genes would most likely contain chromatin in the closed configuration.

d.

The exons of a gene are always expressed in a functional protein.

e.

Activator proteins bind to enhancer sequences and repressor proteins bind to silencer sequences.

f.

The CpG islands upstream of housekeeping genes are unmethylated.

g

Nucleosome location may be changed by a process called ATP-dependent chromatin remodeling.

h

DNA methylation activates gene expression.

Explanation / Answer

1- All are true statements -

a Steroid hormomes are an example of an effector which regulates regulatory transcription factor activity.(true)

b- RNAi is used in eukaryotic cells only to defend against viruses and transposable elements

C- DNA that contains actively transcribed genes would most likely contain chromatin in the closed configuration.

d-The exons of a gene are always expressed in a functional protein.

e- Activator proteins bind to enhancer sequences and repressor proteins bind to silencer sequences.

f-The CpG islands upstream of housekeeping genes are unmethylated.

g- Nucleosome location may be changed by a process called ATP-dependent chromatin remodeling.

h- DNA methylation activates gene expression.