A 45-year-old recently divorced, obese male pharmacist complains of a rapid hear

Question

A 45-year-old recently divorced, obese male pharmacist complains of a rapid heart rate, a 20-pound weight loss in 2 months, and heat intolerance. His pulse rate is 110 beats/minute at rest. The serum T4 level is elevated, confirming the clinical impression of hyperthyroidism. On further questioning, the patient finally admits to taking large doses of exogenous T4 tablets to help him lose weight so that he can more easily remarry.  

A.

-T3

B.

Which of the following cardiovascular factors would be increased?

-TSH -TRH

-T3

B.

Which of the following cardiovascular factors would be increased?

-Muscle creatinine phosphate levels -Plasma norepiphrine levels -Cardiac beta adrenergic receptors -Systemic vascular resistance

Explanation / Answer

1. In patients suffering from hyperthyroidism the level of T4 (Thyroxine) and T3 (Triiodothyronine) will be increased. The level of hormones TSH (Thyroid stimulating hormone) and TRH (Thyrotropin-releasing hormone) which induces the production of T4 and T3 are suppressed.

2. Plasma norepiphrine levels and Cardiac beta adrenergic receptors

In patients suffering from hyperthyroidism will exhibit increased plasma norepiphrine levels (high blood pressure) and cardiac beta adrenergic receptors (increases heart rate, contractibility of cardiac muscles, systolic but not diastolic blood pressure). The levels of muscle creatinine phosphate (muscular dystrophy) and systemic vascular resistance (high cardiac output) will be reduced.

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