RNA-dependent RNA polymerase can be considered a pathogenesis factor for some vi

Question

RNA-dependent RNA polymerase can be considered a pathogenesis factor for some viruses. Why? (select all that apply)

Select one or more:

a. Viral RNA polymerases can produce altered viral genomes, proteins and glycoproteins that can lead to many defective virions.

b. Viral RNA polymerases can use genetic recombination to create novel virulence factors.

c. Viral RNA polymerases can use genetic recombination to create new antigens that cannot be seen by the host immune system.

d. Viral RNA polymerases lack the strict, proofreading fidelity of cellular DNA enzymes.

e. Viral RNA polymerases can produce altered viral genomes, proteins and glycoproteins that can lead to virions resistant to antiviral drugs.

f. Viral RNA polymerases make frequent mistakes during replication.

Explanation / Answer

a. viral RNA pol can use genetic recombination to create noel virulence factors.

c. viral RNA poly can use genetic recombination to create new antigens that cannot be seen by host immune system

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