RNA-DNA hybrids are formed by using messenger RNA for a given gene that is expre

Question

RNA-DNA hybrids are formed by using messenger RNA for a given gene that is expressed in the pituitary and the adrenal glands. The DNA used in each case is the template strand of full-length gene. Based on the figure below, provide an explanation for the different hybrid molecules. Dashed red line indicates DNA. RNA is shown in blue.

6) RNA-DNA hybrids are formed by using messenger RNA for a given gene that is expressed in the pituitary and the adrenal glands. The DNA used in each case is the template strand of full-length gene. Based on the figure below, provide an explanation for the different hybrid molecules. Dashed red line indicates DNA. RNA is shown in blue 2 Adrenal Pnuitary

Explanation / Answer

The mRNA in the two tissues shows that there is differential expression of the gene. The mRNA in the pituitary includes the exons 1,2,3,4,5, and 6 whereas the mRNA in the adrenal gland does not include the exon 3. This shows that the same mRNA undergoes differential splicing in the two tissues and produces different proteins.

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