The consequences of four deletions from the region upstream of the gene DBM1 are
ID: 41971 • Letter: T
Question
The consequences of four deletions from the region upstream of the gene DBM1 are studied to determine the effect on transcription. The normal rate of transcription, determined from study of transcription of the gene without any of the upstream deletions, is defined as 100%. The location of each deletion and the effect of deletions on transcription are shown below. Determine whether the mutations are enhancer sequences, silencer sequence, regulatory promoter or proximal promoter.
1. Deletion A
2. Deletion B
Deletion C
4. Deletion D
Silencer
Proximal Promoter
Regulatory Promoter
Enhancer
1. Deletion A
2. Deletion B
3.Deletion C
4. Deletion D
A.Silencer
B.Proximal Promoter
C.Regulatory Promoter
D.Enhancer
Explanation / Answer
Silencer Deletion B
Proximal Promoter Deletion C
Regulatory PromoterDeletion D
Enhancer-------- Deletion A
A.Silencer Deletion B
B.Proximal Promoter Deletion C
C.Regulatory PromoterDeletion D
D.Enhancer-------- Deletion A
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