1 tgacaatgac catgagcccc aaatatcccc cgggggctta gagcctctca gtgaaaaaca 61 tttccgtga

Question

   1 tgacaatgac catgagcccc aaatatcccc cgggggctta gagcctctca gtgaaaaaca

       61 tttccgtgaa acagaagtct gagaaggtca gggcccagaa taaggctctg acgtctcccc

      121 ccggaggaca gctcagcacc agctcaggct aggccctgac gtgtccccct aaagacaaat

      181 cataagctca gacctccggg aagccaccgg gaaccaccca tttcctcccc atgtttgtca

      241 agccgtcctc aggcgttgac gacaacccct cacctcaaaa aacttttcat ggcacgcata

      301 cggctcaata aaataacagg agtctataaa agcgtgggga cagttcagga gggggctcgc

      361 atctctcctt

Where is TBP going to bind in the above sequence, what is the specific name of this cis-acting element, and what is the general classification of this cis-acting element?

What is the specific protein complex in which TBP resides, and what is its function?

Explanation / Answer

TBP will going to bind this sequence
301 cggctcaata aaataacagg agtctataaa agcgtgggga cagttcagga gggggctcgc , beacuse it contain core DNA sequence TATAAA which is found in TATA BOX.

TATA-binding protein is the name of this cis-acting element .

It binds specifically to a DNA sequence called the TATA box ,this DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters
TBP make  up the TFIID, which is a general transcription factor that makes up part of the RNA polymerase II preinitiation complex

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