Mutation DNA Sequence None 5\' . .A T G G G C G A G G T A T T A T A G.. 3\' A 5\

Question

Mutation DNA Sequence None 5' . .A T G G G C G A G G T A T T A T A G.. 3' A 5' . .A T G G G C G A A G T A T T A T A G.. 3' B 5' . .A T G G G C G A G G T A T A A T A G.. 3' C 5' . .A T G G G C G A G G T A T T A G A G.. 3' The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino acids with no spaces. N- [ ]-c Determine the molecular basis for each mutation and what effect there would be on the protein. Mutation Molecular Basis Effect on Protein

Explanation / Answer

N-Met G E V L-C

A= synonymous (silent mutation)= no change in function

B=N-Met G E V-C (Nonsynonymous,nonsense mutation)= cause truncated protein

C=Met G E V L E (Nonsynonymous, missence mutation)= cause change in protein structure without stop codon

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