2. You will be purifying an LDH isoform from bovine muscle. This isoform is homo
ID: 3515616 • Letter: 2
Question
2. You will be purifying an LDH isoform from bovine muscle. This isoform is homologous to the LDH found in human muscle tissue. Would these bovine and human LDH homologs be considered orthologs, or paralogs?
2. You will be purifying an LDH isoform from bovine muscle. This isoform is homologous to the LDH found in human muscle tissue. Would these bovine and human LDH homologs be considered orthologs, or paralogs?
2. You will be purifying an LDH isoform from bovine muscle. This isoform is homologous to the LDH found in human muscle tissue. Would these bovine and human LDH homologs be considered orthologs, or paralogs?
Explanation / Answer
The bovine and human LDH homologs are considered as orthologs. Orthologs are similar Gene segments that arise due to common ancestry between different species. These othologs have same functions in both species. On the contrary, paralogs have different functions in different species. The LDH homologs are involved in catalytic process of converting lactate to pyruvate in both species.
Lactate + NAD+ -----> Pyruvate + NADH
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