You have been hired by a pharmaceutical company to develop a drug to regulate a

Question

You have been hired by a pharmaceutical company to develop a drug to regulate a specific brain disorder. What is a major physiological roadblock to developing such a drug and how can you design a drug to bypass that roadblock so that the drug is delivered to the brain where it is needed?
You have been hired by a pharmaceutical company to develop a drug to regulate a specific brain disorder. What is a major physiological roadblock to developing such a drug and how can you design a drug to bypass that roadblock so that the drug is delivered to the brain where it is needed?
You have been hired by a pharmaceutical company to develop a drug to regulate a specific brain disorder. What is a major physiological roadblock to developing such a drug and how can you design a drug to bypass that roadblock so that the drug is delivered to the brain where it is needed?

Explanation / Answer

Here physiological roadblock is Blood Brain Barrier. All substances cannot be crossed the blood brain barrier. When we develop a drug to regulate a specific brain disorder, the drug should cross the blood brain barrier to reach brain tissue. So we should design the drug to reach the brain tissue by making it fat soluble. Fat soluble substances dissolve in the cell membrane and cross the blood brain barrier.

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