1- A target cells for hormones has a receptor to which the hormone can bind.?Tru

Question

1- A target cells for hormones has a receptor to which the hormone can bind.?True / False

2-Adrenocorticotropic hormone (ACTH), a water soluble hormone, circulates in the blood bound to a transport protein known as albumin?True / False

3-Lipid soluble hormones bind to_____________ and activate___________.

A- G protein coupled receptors and adenylyl cyclase

B- Tyrosine kinase receptors and gene expression

C- Intracellular receptors and gene expression

D- G protein coupled receptors and phospholipase C

4- A significant decrease in the secretion of Aldosterone will produce dehydration?True / False

5- The pituitary gland is attached to the _________ by the __________.

A- Hypothalamus and Pars tuberalis

B- Hypothalamus and Infundibulum

C-Median eminence and Pars distalis

D-None of the above

6- Which type of anterior pituitary cell produces human growth hormone?

A- Corticotrophs

B- Somatotrophs

C- Thyrotrophs

D- Gonadotrophs

E- Lactotrophs

7-Which of the following sequence of events is correct regarding the mechanism of protein hormone action?

1. Activation of adenylate cyclase; 2. Binding of hormone to a membrane receptor;

3. Activation of the G protein; 4. Formation of cAMP; 5. Activation of a protein kinase

A- 1, 2, 3, 4 and 5

B- 2, 3, 1, 5 and 4

C- 3, 1, 2, 4 and 5

D- 2, 3, 1, 4 and 5

E- 1, 4, 2, 5 and 3

8-The hormones released from the anterior pituitary gland are controlled or regulated by___________?

Muscle contraction

Action potential from the thalamus

Hormones released from the hypothalamus

Chemical changes in the cerebrospinal fluid (CSF)

9- Which statement is INCORRECT about the mechanism of action of ADH (anti-diuretic hormone or vasopressin) in the kidney?

A- ADH activates V2 receptors

B- The activation of vasopressin receptors by ADH decreases cAMP

C- ADH promotes an increase in the number of water channels (aquaporin 2)

D- The activation of vasopressin receptors activates protein kinase A (PKA)

10-What statement is CORRECT concerning Autocrine hormones?

A- They are secreted into the circulation

B- They act on a neighboring cell

C- They act on the cell that secrets them

D- None of the above

Explanation / Answer

1 TRUE

hormone usually affects only a limited number of cells, which are called target cells. A target cell responds to a hormone because it bears receptors for the hormone.

2.false

Lipid soluble hormones circulates in to the blood stream

3 C

Lipid soluble hormones binds to intracellular and alter gene expression

4 true

5 b

The pituitary gland (hypophysis) is attachedto the bottom of the hypothalamus by a slender stalk called the infundibulum.

6 B somatotrophs

7 D 2 3 1 4 5

8The release of hormones from the anterior pituitary gland is generally controlled by hormones from the hypothalamus.

9 b

10 c

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