BSc 3850.101 EXAM 4 Name Choose the BEST answer for each question. Question valu

Question

BSc 3850.101 EXAM 4 Name Choose the BEST answer for each question. Question value = 1.5 pts. I. Which of the following is NOT associated with normal cognitive aging? a. loss of dendritic spines b. reduction in synapses c. fragmented, lost myelin d. neuronal cell death e. reduction in neurotransmitter synthesizing enzymes 2. Before PET scans could be used to detect amyloid accumulation, Alzheimer's could only be confirmed by b. a skilled neurologist c. biopsy d. blood test e autopsy 3. Two obvious structural changes to the brain that occurdring normal aging and are exaggerated in Alzheimer's disease include a. brainstem swelling&spinal; cord b. hypothalamic atrophy& pineal gland enlargement c. mammillary body protrusion&fimbria; thinning d. hippocampal delamination & striatal migration e. enlarged ventricles & cortical thinning 4. The nuclei in the basal forebrain that produce this neurotransmitter are one of the first affected by neurodegeneration in Alzheimer's disease. a. Norepinephrine b. Acetylcholine c. Oxytocin d. Dopamine e. Serotonin The Mini-Mental Status Exam and the Clock Drawing Test are two short, but effective assessments of 5· a. cognitive decline b. stress disorders c. amygdala damage d. personality changes e. mood destabilization 6. True or False: Amyloid plaque formation in Early-onset Alzheimer's disease has a genetic basis. a. True b. False

Explanation / Answer

Hi,
As per our regulation, only first question is to be answered. I have answered a few of them for your help.
1. a
loss of dendritic spine is associated with Alzemer's condition. The loss of neuritic spine is associated with normal aging. All other options like reduction in synapse, reduction in neurotransmitter levels and loss of myelin associated memory loss are all associated with normal cognitive aging.
2. Biopsy. It is used to determine the disease or disorder in the body. Autopsy on the other hand is done to determine the cause of death.
4. b. Acetylcholine: It is a neurotransmitter essential for processing memory and learning, is decreased in both concentration and function in patients with Alzheimer's disease.
6. True. A immune system mutation can increase the chances of plaque formation.

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