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BSA DILUTIONS Set up Bovine Serum Albumin dilutions (prepared in 0.01% SDS) to p

ID: 192297 • Letter: B

Question

BSA DILUTIONS

Set up Bovine Serum Albumin dilutions (prepared in 0.01% SDS) to provide a standard curve for future lab experiments. Each group will be given 1 mL ampoules of 2 mg/ml BSA. We will have a few extra ampoules in case of accidents. Make your dilutions in 1.5 mL eppendorf tubes.

Final BSA Concentration

Concentration of BSA Stock

Desired Volume

Volume of Stock (to be added)

Volume of 0.01% SDS (to be added)

5µg/100µL

100µL

10µg/100µL

100uL

20ug/100uL

100uL

30ug/100uL

100uL

40ug/100uL

100uL

50ug/100uL

100uL

60ug/100uL

100uL

70ug/100uL

100uL

  

Final BSA Concentration

Concentration of BSA Stock

Desired Volume

Volume of Stock (to be added)

Volume of 0.01% SDS (to be added)

5µg/100µL

100µL

10µg/100µL

100uL

20ug/100uL

100uL

30ug/100uL

100uL

40ug/100uL

100uL

50ug/100uL

100uL

60ug/100uL

100uL

70ug/100uL

100uL

Explanation / Answer

Stock BSA solution = 2mg/ml

to make 70 g / 100 l

2000 g BSA presents in 1000 l

70 g BSA presents in 1000 X 70 / 2000 = 35 l

thus we need 35 l BSA stock solution and ( 100-35) l= 65 l of 0.01% SDS.

The other concentation were also calculated like this.

Fnal BSA Concentration

Concentration of BSA Stock

Desired Volume

Volume of Stock (to be added)

Volume of 0.01% SDS (to be added)

5µg/100µL

2 mg/ml

100 µL

2.5µL

97.5µL

10µg/100µL

2 mg/ml

100 µL

5µL

95µL

20µg/100µL

2 mg/ml

100 µL

10µL

90µL

30µg/100µL

2 mg/ml

100 µL

15µL

85µL

40µg/100µL

2 mg/ml

100 µL

20µL

80µL

50µg/100µL

2 mg/ml

100 µL

25µL

75µL

60µg/100µL

2 mg/ml

100 µL

30µL

70µL

70µg/100µL

2 mg/m

100 µL

35 µL

65 µL

Fnal BSA Concentration

Concentration of BSA Stock

Desired Volume

Volume of Stock (to be added)

Volume of 0.01% SDS (to be added)