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A particular group of similar cells responds to 2 different hormones that are se

ID: 3474805 • Letter: A

Question

A particular group of similar cells responds to 2 different hormones that are secreted when blood sugar falls. Hormone A is lipid-soluble and the Hormone B is water-soluble. Hormone A is released from its gland directly in response to a drop in blood sugar. Hormone B is released at the end of a pathway that involves the release of 2 other hormones prior to the release of hormone B. Without identifying specific hormones, contrast the homeostatic regulatory pathways that would involve the release of these 2 hormones and the restoration of normal blood sugar. Consider the water vs. lipid solubility and the different ways in which each hormone release is regulated in your answer.

Explanation / Answer

Hormone A is secreted directly from the gland in response to fall in blood glucose levels and it is lipid soluble. Therefore, blood glucose levels exert a negative feedback mechanism on the secretion of hormone A.

Hormone B is water soluble and is released at the end of a metabolic pathway. Two other hormones are released prior to hormone B in this pathway. Each of these hormones act as an allosteric regulator for the secretion of hormone B.

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