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A. ifirst. Which administration route enables a drug to reach the A. intravenous

ID: 3464369 • Letter: A

Question

A. ifirst. Which administration route enables a drug to reach the A. intravenous 25. Of the following, ?.oral C. intraperitoneal D. subcutaneous cocaine -uppression effects of locally applied novocaine, lidocaine, and rectlyot Michael Caine - are produced because these drugs 26. The pain-su block N channels in the axons of pain-transmitting neurons block ca channels in the axons of pain-transmitting neurons C. Ca2 channels in the axon terminals of pain-transmitting Dlock postsynaptic opioid receptors, which blocks the ascending pain message neurons D. E. A& EB F. B & D G. A, B, C &D; 27. Which action produces a change (i.e., increase or decrease) in synaptic neurotransmitter activity different from the other three? A. inhibition of neurotransmitter release B. inhibition of neurotransmitter reuptake C. inhibition of enzymatic breakdown of neurotransmitter D. facilitation of neurotransmitter synthesis Selective permeability is the characteristic of A. 28. B. C. D. voltage-dependent ion channels that makes them open and close at particular membrane potentials neuronal membranes that allows some ions to pass through more readily than others natural selection that enables only certain traits (the most adaptive) to be passed on to future generations postsynaptic receptors that enables only neurotransmitters with a particular shape to bind to them conduction occurs as charge 29. During he dendrites/soma to the axon hillock. A. non-decremental B. C. reiterative D. non-multiplicative E. progressive F. regressive decremental

Explanation / Answer

Answer 25. Option A intravenous

Intravenous route is the fastest route of all to reach the brain as in this route drug is transported through blood from the veins to the heart and then through arteries to brain.

Answer 26. Option b

Pain supression effects of locally applied lidocain is by blockade of Na+ channels. While intravenous use of lidocaine or other anasthetic is found to act through opioid receptors but not if given locally.

Answer 27. Option c

Change in synaptic transmission occurs after inhibition of braekdown of neurotransmitter thus optimal amount of neurotransmitter is available for transmission and signal transduction.

Answer 28. Option b

Selective permability is characteristics of neuronal cell membranes.some solutes cross membranes freely,some cross with assistance and others do not cross at all. Crossing or permeability depends on lipid solubility,some lipophilic substances freely move aross the membrane by passive diffusion,most small ions requires assistance is specific protien carries while other do not permeate at all.

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