Previous studies have shown that supplementing the diet with oat bran may lower

Question

Previous studies have shown that supplementing the diet with oat bran may lower serum-cholesterol levels. However, it is not known whether the cholesterol is reduced by a direct effect on oat bran or by replacing fatty foods in the diet. To address the question, a study was performed to compare the effect of dietary supplementation with high-fiber oat bran (87g/day) to dietary supplementation with a low-fiber refined wheat product on the serum cholesterol of 20 healthy participants ages 23-49 years. Each subject had a cholesterol lelvel measured at baseline and then was randomly assigned to receive either a high-fiber or a low-fiber diet for 6 weeks. A 2-week period followed during which no supplements were taken. Participants then took the alternate supplement for a 6-week period. The results are shown in table below.

Question 1
Test the hypothesis that the high-fiber diet has an effect on cholesterol levels as compared with baseline (report your results as p>.05 or p>.05).

Explanation / Answer

paired sample test wil be used

difference in mean = 14

since 95 % confidence interval of difference is (-21,-7) and 0 is not present

hence we reject the null and

p-value < 0.05

we conclude that he high-fiber diet has an effect on cholesterol levels as compared with baseline

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