S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression.

ID: 3243010 • Letter: S

Question

S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression. A study randomly assigned smokers who wanted to quit smoking to one of three groups: a low dose of SAMe, a high dose of SAMe, or a placebo. After 8 weeks of treatment and behavioral smoking cessation intervention, smoking abstinence was assessed biochemically. Here are the findings

(a) The percent of subjects abstaining from smoking in the placebo group is about

(b) The percent of subjects abstaining from smoking in the placebo group is:

NOTE: The numerical values in this problem have been modified for testing purposes.

Abstinent Still smoking Placebo 9 34 Low-dose SAMe 9 34 High-dose SAMe 7 36

(a) The percent of subjects abstaining from smoking in the placebo group is about

16.3 % 20.9 % 19.4 %

(b) The percent of subjects abstaining from smoking in the placebo group is:

about the same as the percent of subjects abstaining from smoking in the high-dose SAMe group lower than the percent of subjects abstaining from smoking in the high-dose SAMe group higher than the percent of subjects abstaining from smoking in the high-dose SAMe group

Explanation / Answer

a) Percent of subjects abstaining from smoking in the placebo group = 9/(9 + 34) = 9/43 = 20.9%

Option B is correct.

b) For high dosage, percentage = 7/(7 + 36) = 7/43 = 16.3%

So,

The percent of subjects abstaining from smoking in the placebo group is higher than the percent of subjects abstaining from smoking in the high-dose SAMe group.

Option C is correct.

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S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression.

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S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression.

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