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S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression.

ID: 2907098 • Letter: S

Question

S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression.

A study randomly assigned smokers who wanted to quit smoking to one of three groups: a low dose of SAMe, high dose of SAMe, or a placebo.

After 8 weeks of treatment and behavioral smoking cessation intervention, smoking abstinence was assessed biochemically.

Here are the findings:

The component of the chi-square statistic for the cell of subjects abstaining from smoking in the placebo group is about

0.0034.

6.33.

33.337.

0.07.

Abstinent Still smoking TOTALS Placebo    7 33 40 Low-dose SAMe    7 33 40 High-dose SAMe    5 35 40 TOTALS 19    101    120

Explanation / Answer

Expected frequency for cell of subjects abstaining from smoking in the placebo group

= (40*19)/120

= 6.33

Hence,

Chi square component = (7 - 6.33)2 / 6.33 = 0.07

Option D is correct.