Looking for detailed explanations for Biochem questions: 1. Focusing on the 8 ma
ID: 3166817 • Letter: L
Question
Looking for detailed explanations for Biochem questions:
1. Focusing on the 8 main reactions of the TCA cycle, how many tricarboxylic acids are substrates for enzyme catalysis?
A.
One.
B.
Two.
C.
Three.
D.
Four.
E.
Five.
2. The following enzymes all use NAD+ for oxidation, except:
A.
Alpha-Ketoglutarate Dehydrogenase complex.
B.
Isocitrate Dehydrogenase.
C.
Succinate Dehydrogenase.
D.
Malate Dehydrogenase.
E.
All of these enzymes use NAD+
Figure 1
Four of the five intermediates below are true intermediates in the TCA. One of the five is not an intermediate in any reaction in biochemistry.
3. Which intermediate in Figure 1 releases CO2 concurrent with oxidation?
A.
1
B.
2
C.
3
D.
Intermediates 1 and 2.
E.
Intermediates 1, 2, and 3.
4. Which intermediate is the product of the isocitrate dehydrogenase reaction?
A.
1.
B.
2.
C.
3.
D.
4.
E.
5.
A.
One.
B.
Two.
C.
Three.
D.
Four.
E.
Five.
COO CH2 CH2 COO HO-C-H CH2 COO COO COO COO CH2-S-CoA CH2 CH HO-C-COOHC-COO CH CH2 HO-C-H COO COO COO COO 2. 4Explanation / Answer
2) the correct option is option (c) succinate dehydrogenase is the enzyme which donot require NAD(+) for oxidation but uses FAD..!!
3) the correct option is option (e) all these intermediate 2(iso-citrate)and 3(alpha-ketogluterate)all these will give Co2 while in the reaction...
4) the correct option is option (c) intermediate 2 iso-citrate is being acted upon by the enzyme called iso-citrate dehydrogenase which release one CO2 and form alpha-ketogluterate which is intermediate (3)
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