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A) the allele frequency of A2 after one generation of selection is? 4) Mudflat o

ID: 3163549 • Letter: A

Question

A) the allele frequency of A2 after one generation of selection is? 4) Mudflat organisms in the Bay of Fundy experience large fluctuations in salinity due to freshwater run off. Tolerance to low salinity is linked to a gene with the following fitness values: w11 0.5; w12 0.5; and w22 1.0. [Hint: refer to Box 7.2 on page 238-9] a) If the population allele frequency of the A2 allele is q 0.85, predict the frequency after one generation of selection. b) Now assume a massive migration of 20% of the population enters the Bay of Fundy from the open ocean where the frequency of the A2 allele (q) is zero. Given a starting allele frequency of q 0.95, what would be the new frequency of the A2 allele be following one generation of selection and migration?

Explanation / Answer

4a) from the given value we know that genotype frequency:

p^2, 2pq, q^2 and relative fitness

W11, W12, W22

taking highest scale factor 1 and q=.85 we get p=1-.85=.15

now average fitness=W'=P^2W11+2pqW12+ q^2 W22=.15^2*.5+2*.15*85*.5+.85^2*1=.86125

frequency after 1 gen of selection:

p'=p^2W11/w'+pqW12/W'=.0130624+.07402032=.087082

q'=q^2W11/W'+pqW12/W'=.41944+.07402032=.49346

b) after selection but before migration p*=p(1/1-q^2)s=.5125s

after migration p'=p(1-m)/1-q^2s=.05(1-.2)=.04

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