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I have been given mock results from a PCR test on blood samples taken from kidne

ID: 31558 • Letter: I

Question

I have been given mock results from a PCR test on blood samples taken from kidney recipient patients and their donors. The PCR reaction can detect single copies of viral DNA. I have been asked to determine whether 5 patients have been infected with either human herpesvirus 6 (HHV6) or human cytomegalovirus (HCMV) following kidney transplants. I have results for patients pre-transplantation and 1/3 weeks post-transplantation.

The results are as follows:

Donors:

Recipients:

Answers: I am guessing that Patient A was re-infected by donor A. Patient B was neg for both viruses, developed HHV6 week 1 but this test was neg week 3 & instead positive for HCMV

Explanation / Answer

I get the feeling that there's something we should probably know from your textbook or notes that you have not included. As-is, here's my best shot:

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