07. A patient comes in complaining of the following symptoms: . Increase in food
ID: 301821 • Letter: 0
Question
07. A patient comes in complaining of the following symptoms: . Increase in food consumed, but no appreciable weight gain. 1 alyolyss . Decreased fat content in adipose and liver cells. high FA breakdow ody thines it's statira Increased B-oxidation both in the presence and absence of insulin. Decreased downregulation of B-oxidation in response to insulin. . Other insulin responses are normal. Based on these symptoms, I conclude that the patient has a mutation in one specific enzyme which enzyme? What is the basis for this conclusion?Explanation / Answer
Acetyl CoA converts to Malonyl-CoA (McoA) by Acetyl-CoA carboxylase. Malonyl CoA regulates inhibit beta-oxidation. If McoA does not produce, the beta-oxidation will continue.
Therefore, Acetyl-CoA carboxylase must have mutated.
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