3. B-lactam drugs, like penicillin, were once considered to be very successful a

Question

3. B-lactam drugs, like penicillin, were once considered to be very successful antimicrobial agents however, the rapid increase in B-lactam resistant bacteria leaves people wondering whether B-lactam drugs will be useful in the years ahead. For some time, scientists have been working on ways to combat penicillin resistance in bacteria and have developed a compound that may help. When used with penicillin this compound can kill a penicillin-resistant bacterium, but the compound alone has no effect on penicillin-resistant organisms. Knowing the mechanism of penicillin resistance explain how this compound might work? 13 pts

Explanation / Answer

These drugs are called Antibiotic adjuvents. Avibactum,Tavobactum and Phenylalanine arginine beta naphthylamide are some good examples.

They show their activity in any of three ways given below

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