The drug AZT was the first effective treatment for AIDS. An important medical ex

Question

The drug AZT was the first effective treatment for AIDS. An important medical experiment demonstrated that regular doses of AZT delay the onset of symptoms in people in whom HIV is present. The researchers who carried out this experiment wanted to know the following:

• Does taking either 500 mg of AZT or 1500 mg of AZT per day delay the development of AIDS?

• Is there any difference between the effects of these two doses?

The subjects were 1200 volunteers already infected with HIV but with no symptoms of AIDS when the study started.
(a) Outline the design of the experiment.

(b) Describe briefly how you would use a table of random digits to do the randomization required by your design.
Then use Table B beginning at line 110 to choose the first five subjects for one of your groups.

Explanation / Answer

I dont understand how the above questions are answered.

How do we calculate if taking either 500 or 1500 mg of AZT per day will delay the development of AIDS? Is is P(a or b) = P(a)+ P(b)-P(a and b) ? Could you help me set it up?

My question is the same, except it only had part a. However, I guess I thought we were supposed to answer the questions posed.

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