PLEASE ANSWER ALL 3 QUESTIONS 1) A doctor performs exome sequencing on a number
ID: 275043 • Letter: P
Question
PLEASE ANSWER ALL 3 QUESTIONS
1) A doctor performs exome sequencing on a number of autistic patients from different families. He uses a database to compare their genomes to those of healthy individuals. What type of exome sequencing is he performing?
Multiple Choice
Twin studies
Trio analysis
Recessive analysis
Multiple unrelated affected subjects
2) What type of treatment might be useful in cases of autism involving mutations in neurexins and neuroligins?
Multiple Choice
Treatments that draw neurons closer together
Treatments that prevent synaptic pruning
Treatments that decrease the interaction between two neurons
Treatments that increase the amount of serotonin in synapses
3) Mood disorders are based in part on genetic factors. Choose the best term to complete each of the following sentences about mood disorders.
1. In the mood disorder called (Click to select) major depressive disorder bipolar disorder hypomania , people experience periods of mania.
2. Selecting antidepressants based on genotype is an example of a form of genetic testing called (Click to select) pharmacogenetics exome sequencing trio analysis I.Q. testing .
3. Bipolar disorder with (Click to select) mental retardation muscle dysmorphia schizophrenia hypomania may appear to be depression.
4. Bipolar disorder affects approximately (Click to select) 20.6 8.6 32.6 2.6 percent of the population.
5. Deficiency of the neurotransmitter (Click to select) acetylcholine serotonin norepinephrine dopamine is considered a likely cause of depression.
Explanation / Answer
1. Recessive analysis
As recessive phenotypes have disease causing variants.
2. Treatment that increase the amount of serotonin on synapses.
3.
1. Bipolar disorder
2. Pharmacogenetics
3. Hypomania
4. 2.6
5. Serotonin
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