1. A patient is prescribed drug for the treatment of his prostate cancer that bl
ID: 267942 • Letter: 1
Question
1. A patient is prescribed drug for the treatment of his prostate cancer that blocks testosterone from binding to its intracellular receptor. Which of the following drugs has this mechanism of action? A. Flutamide B. Tamoxifen C. Leuprolide D. Sunitinib
2. Major serious effect associated with the long-term use of an aluminum-containing antacid include: A. Dementia B. Diarrhea C. Kidney stones D. Phosphate depletion E. Severe alkalosis
3. Which of the statements best describes why patient who fail to respond to first-line chemotherapy have a decreased likelihood of a response to a second-line regimen? A. Decreased performance status of patient B. Tumor cell resistance caused by multidrug resistance gene C. Tumor cell resistance caused by selection of resistant clones D. Increased tumor burden E. All of the above
4. A 29-year-old woman develops an exfoliate rash with painful joints, anemia, and nephritis while being treated for a first episode of a urinary tract infection. Which of the following drugs is responsible for these effects? A. Ciprofloxacin B. Polymyxin B C. Trimethoprim-Sulfamethoxazole D. Nitrofurantoin
5. Which of the following medications, when taken prior to eating, is especially effective for correcting postprandial hyperglycemia after a high-carbohydrate meal, so that hypoglycemia post dosing is minimized? A. Acarbose B. Glyburide C. Glitazone D. Tolbutamide
6. Which of the following best describes the outcome resulting from the use of 17alpha-alkylated testosterone to enhance athletic performance? A. Decreased hepatotoxicity compared with testosterone esters B. Decreased spermatogenesis C. Reduced effects on serum lipid levels compared with testosterone esters D. Cannot be converted to DHT, which reduces effects on prostate size
7. Which one of the following is most likely to interfere with cytochrome P450 metabolism? A. Cimetidine B. Ranitidine C. Sucralfate D. Metoclorpramide
8. A 28-year-old patient is newly diagnosed with active TB. Which of the following drug combinations should be initiated in this patient? A. Ethambutol, pyrazinamide, rifampin, streptomycin B. Ethambutol, isoniazid, rifampin, streptomycin C. Ethambutol, pyrazinamide, rifampin, streptomycin D. Isoniazid, rifampin, pyrazinamide, ethambutol
Explanation / Answer
Answer:
1.
Flutamide blocks testosterone from binding to its intracellular receptor.It is used for the treatment of prostate Cancer.
Hence,option (a) is correct answer.
2.
Major serious effect associated with the long-term use of an aluminum-containing antacid include phosphate depletion.
Hence,option(D) is correct answer.
3.
All of the statements are true
Option (e) is correct.
4. The drug which is responsible for these effects is:
Trimethoprim-Sulfamethoxazole.
Hence, option (C) is correct.
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