Mutant forms of tumor-suppressor genes typically behave in a recessive manner. H

Question

Mutant forms of tumor-suppressor genes typically behave in a recessive manner. However, a recent study of patients with multiple myeloma revealed that approximately 10% of these patients have one normal p53 gene and one mutant p53 gene. If it is the mutant p53 gene that is responsible for this group's cancer, which of the following statements would most likely be TRUE? A. The mutant p53 gene is having epigenetic effects in these patients. these patients but rather an oncogene repair pathways. these patients. B. The p53 gene is not a tumor-suppressor gene in O C. The mutant p53 gene most likely is involved in DNA- D. The mutant p53 gene is being overexpressed in E. The p53 gene can act in a haploinsufficient manner

Explanation / Answer

Ans) Option C

The Mutant p53 gene most likely is involved in DNA-repair pathways.

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