Question VIlI. The complement system has been a target for the development of co

Question

Question VIlI. The complement system has been a target for the development of compounds that compound is an inhibitor of the C5a receptor, a receptor expressed on macrophages, dendritic cells, and granulocytes. the resulting statements (79-82) as either factually correct (true) or incorrect (false)] 79. the recruitment of macrophages and neutrophils to the sites of autoantibody binding. 80. cell lysis by the membrane attack complex. 81. cell uptake by phagocytic cells bearing complement receptors. This C5a receptor inhibitor would function to prevent [complete the sentence and assess

Explanation / Answer

I think the correct answer must be (79) prevent the recruitment of macrophages and neutrophils to the sites of autoantibody binding.

Explanation:-

The 5a component of complement protien is a potent inflammatory madiators and responsible for many autoimmune disorders.

- In autoimmune disorders , there occurs formation of self antibodies celled autoantibodies which causes imflammatory reaction and disease.

- the C5a inhibitors will prevent binding of C5a protiens to its receptor and blocks its inflammtory function.

- so the inhibitors prevent reqruitment of inflammtory cells like Neutrophils and Macrophages to the site of autoantibody binding.

Hopefully it helps if problems arises plz comment thanks.

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