Hi, hell please (7) You work at a company that is using nanotechnology to build

Question

Hi, hell please

(7) You work at a company that is using nanotechnology to build small machines. Your group's project is to build a tiny machine that can carry out translation of a protein without a ribosome. It seems to work! Your colleagues mix an mRNA and an abundance of charged tRNAs in a test tube full of the wee tiny translation machine. A protein product is generated The correct amino acids are joined together in the correct order for this protein prodtuct, but the protein product is nonfunctional. At the next meeting of the research group, your boss turns to you. She says, "You're our geneticist. What might be missing in our system that is preventing the synthesized proteins from having an activity?" You have at least 5 ideas. You say (5 points)

Explanation / Answer

The nano-machine generates the primary sequence of the protein. However, the protein needs 3D structure to function.

i. We may use proper buffer solution which allows for the correct folding of the protein

ii. The protein may require the help of a chaperone for its folding

iii. The protein may require processing (proteolytic cleavage) for its activity.

iv. The protein may require processing (post-translational modifications) for its activity.

v. The protein may require an additional factor such as a cofactor (a non-protein component) for its activity.

We need to check for all these probabilities.

Related Questions

Navigate

• Browse (All)
• Browse H
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.