Hi, can you please help me with these question. Show step by step how you got th

Question

Hi, can you please help me with these question. Show step by step how you got the answer so I can understand it thank you!

1. Describe how DNA polymerase finds the correct place to begin polymerizing a new strand of DNA merfinds the coret plece to beg olymerizing a strand polymerase of RNA 3. Draw structures that clearly show the chemical reaction catalyzed by DNA polymerase You must use arrows to show clearly what electrons are involved in the reaction (meaning what bonds are broken and what bonds are formed). Be neat with your drawing because if I cannot interpret your meaning then your answer will not receive credit. 4. What is the bacterial protein that interacts with RNA polymerase to aid in its binding to a promoter sequence 5. How are bacterial and eukaryotic promoters different?

Explanation / Answer

Answer- (1) There is origin of replication site in DNA and initial most event in replication is addition of RNA primer, these help DNA polymerase to initiate replication.

(2)RNA polymerase also find correct place for transcription because there is sequences on DNA which act as start signal for example in bacteria sequence is 5' TATAAT 3' while sequence in mammals is 5' TATAAA 3'

(4) This is the sigma factor, protein which aid in binding of RNA polymerase to promoter sequence.

(5)Bacterial and eukaryotic promoters are different, in bacteria there is TATA box or pribnow box with sequence of 5' TATAAT 3' while in eukaryotes like mammals contain Hogness box with sequence of 5' TATAAA 3'

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