Question 2 (50 points): Refer to the article “Establishing an Invitro Model for

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Question 2 (50 points): Refer to the article “Establishing an Invitro Model for High-Throughput Screening and Risk Assessment of Torsadogenic Drugs”, in which induced pluripotent stem cells (iPSC) are used to develop the model.

2A. (25 points, 250 words or less) Describe in conceptual detail how one can use genetic engineering methods to make iPSC from somatic cells, such as skin cells.

2B. (25 points, 250 words or less) Some scientists and clinicians hope to develop iPSC for treatment of various degenerative diseases. Discuss the ethical and therapeutic implications of using iPSC instead of embryonic stem cells for treatment in humans.

Explanation / Answer

Question 2 (50 points): Refer to the article “Establishing an Invitro Model for

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