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please answer all the questions answering only one question as not helpful : Que

ID: 262149 • Letter: P

Question

please answer all the questions answering only one question as not helpful :
Question 3

A required costimulatory signal provided by T cells to B cells as part of the help process that leads to antibody secretion is...

B7-CTLA4

B7-CD28

CD40L-CD40

IL2-CD25

CD40-CD25

Question 4

In the absence of T cell help, B cells will usually produce only one antibody isotype. Which one?

IgA

IgD

IgE

IgG

IgM

Question 5

Th17 cells are often referred to as supporting barrier defenses. This is accomplished by secreting various cytokines. One of the cytokines that Th17 cells are famous for producing is able to support barrier defenses without inducing damaging inflammation. Which one?

IL-2

IL-4

IL-5

IL-17

IL-22

Question 6

This cytokine is essential for the initiation of Th17 cell differentiation.

IL-12

IFN-gamma

IL-6

IL-5

IL-4

Question 7

Adjuvants are capable to enhancing the antigenicity of an antigen by...

Slowly releasing antigen from a site of injection.

Enhancing antigen uptake by antigen presenting cells

Providing signal zero to antigen presenting cells

All of the above are correct

None of the above are correct

Question 8

One difference between variolization and the vaccination process that was developed by Edward Jenner is...

Variolization involves direct exposure of humans to a fully virulent form of a deadly pathogen whereas vaccination does not.

Variolization resulted in a dead rate of approximately 3% whereas vaccination resulted in a 0% death rate.

Variolization required obtaining exudate from the lesions of a smallpox infected person whereas vaccination required obtaining exudate from cowpox-infected cattle.

All the above are correct.

None of the above are correct.

Question 9

Macrophages are plastic in the sense that they can be driven to polarize their function (M1 versus M2) depending on their environment. What is a function of M2 polarized macrophages?

They facilitate repair of tissue damage that might be caused by worms.

They suppress inflammation and the maintenance of M1 macrophages once an infection has been stopped.

They secrete cytokines that can suppress T effector cell function.

All of the above are correct.

None of the above are correct.

Question 10

Which one of the following cytokines is not suppressive of Th17 cell responses?

IFN-gamma

IL-4

TGF-beta

IL-10

IL-1

B7-CTLA4

B7-CD28

Explanation / Answer

3- Answer is CD40- CD40L

4- IgM

5- IL-17

6- IFN gamma

7- All of them are correct.

8- All of the above are correct

9- They facilitate repair of tissue damage caused by worms.

10- IFN gamma