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1. A gene X contains the following piece of sequence close to the transcription

ID: 261514 • Letter: 1

Question

1. A gene X contains the following piece of sequence close to the transcription starting site 5' - CCTCCAAAGAAGAAAAGGAAGGTC 3 A. (5 pts) Write the mRNA sequence, translate into amino acid sequence. B. (5 pts) You are using immunofluorescence staining to visualize this protein in the cell. Predict the subcellular localization of this protein C. (5 pts) Design an experiment to test the hypothesis that this signal sequence is sufficient to direct protein X to the destination D. (5 pts) In a point mutation the underlined "A" is changed to "C Re-write the amino acid sequence, and predict the subcellular localization of the mutated protein.

Explanation / Answer

1.  

5' - CCT CCA AAG AAG AAA AGG AAG GTC - 3'

3' - GGA GGU UUC UUC UUU UCC UUC CAG - 5'. - mRNA

GGA - glycine

GGU - glycine

UUC - phenylalanine

UUC - phenyalanine

UUU - phenylalanine

UCC - serine

UUC - phenylalanine

CAG - glutamine.

3' - gly - gly - phe - phe - phe - ser - phe - gln - 5''. - protein