Death cap mushrooms produce a substance called alpha-amanitin. Alpha-amanitin ef

Question

Death cap mushrooms produce a substance called alpha-amanitin. Alpha-amanitin efficiently blocks synthesis of mRNA, but not of tRNA or rRNA in eukaryotic organisms. How is that possible?

a.Alpha-amanitin efficiently interferes with RNA polymerase III, but not RNA polymerase I and II.
b.Alpha-amanitin efficiently interferes with the action of RNA polymerase II, but not RNA polymerase I or III.
c.Alpha-amanitin efficiently interferes with the action of RNA polymerase I, but not RNA polymerase II or III.
d.Alpha-amanitin efficiently blocks the action of one or more basic transcription factors.

Explanation / Answer

b.Alpha-amanitin efficiently interferes with the action of RNA polymerase II, but not RNA polymerase I or III.

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