Intravenous administration on exogenous immunoglobulin is a widely used therapy

Question

Intravenous administration on exogenous immunoglobulin is a widely used therapy for autoimmune disorders that involve the production of antibodies against self-antigens. Researchers have discovered that the presence of sialic acids on the infused immunoglobulins is critical for the inhibition of autoantibody production in the patient's own B-cells. Which of the following receptors could potentially be responsible for the inhibition of antibody production by B-cells, given this finding?

a.FcyRIIB

b.CD22

c.PD-1

d.CD40

e.BTLA

Explanation / Answer

I believe the correct option to be

B) CD22

as this is the receptor responsible for prevention of overactivation of immune system and prevents auto immune disorder.

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