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Two healthy people have a child expressing a genetic condition caused by a domin

ID: 259178 • Letter: T

Question

Two healthy people have a child expressing a genetic condition caused by a dominant allele. How can this situation be explained?

Only infidelity.

Both parents cannot be free from the disorder- one of them will certainly display the symptoms later in life.

The disease arose spontaneously in the child due to a germ cell mutation in one of the parents, so the child is the result of a de novo mutation.

The child is certainly not the biological child of the couple described

The mutation arose spontaneously in the child due to a somatic mutation in the child

Duchenne Muscular Dystrophy is an XLR genetic disorder in which patients do not live to reproduce. Which of the following represents the most likely assumption?

All cases must occur in relatives

Successive generations of a family will continue to have more and more cases over time

The mutant allele is passed down the generations only through carrier females.

Each patient certainly has had at least one affected family member in a previous generation

Homozygous affected females may be seen in some families with consanguineousmarriages.  

A.

Only infidelity.

B.

Both parents cannot be free from the disorder- one of them will certainly display the symptoms later in life.

C.

The disease arose spontaneously in the child due to a germ cell mutation in one of the parents, so the child is the result of a de novo mutation.

D.

The child is certainly not the biological child of the couple described

E.

The mutation arose spontaneously in the child due to a somatic mutation in the child

Explanation / Answer

1) The correct answer is option C that is The disease arose spontaneously in the child due to a germ cell mutation in one of the parents, so the child is the result of a de novo mutation..

2) The correct answer is option C that is The mutant allele is passed down the generations only through carrier females.

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