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Fill in the blanks 1-28 Word bank: A. Separase B. APC C. P53 D. Cdc25 E. Chromos

ID: 255834 • Letter: F

Question

Fill in the blanks 1-28

Word bank:

A. Separase

B. APC

C. P53

D. Cdc25

E. Chromosomes

F. Microtubule associated proteins

G. MAP signaling cascade

H. Cyclin production

I. S Cdk

J. Ubiquitinate and destroy cyclins

K. Securins

L. Wee1

M. Condensins

N. Deploy Cdk inhibitors

O. Apoptosis

P. P21 gene

Q. Activates DNA replication

R. P21

S. Cell proliferation genes

T. G1 and G1/S Cdk Complexes

U. Block cyclin synthesis

V. Cohesions

W. Release from DNA

X. Microtubule destabilization

Y. Retinoblastoma Protein (Rb)

Z. Prevents re-replication

E?losive Entrance into M-phase 21. Entering Gs phase: 22. 18. Phosphorylates and destabilizes 23 Leads to activatesand activates 19. M Gak Bind, intibit Entering Anaphase 25. chromosomes ubiquitinates cleaves 20. inhibit 28 Entering Gs phase Go (Double check S phase) __ If DNA damage ONA Damage Ireparable DNA damage? Stabilized and To Exit G phase: 14 Binds activated 4 Mitogens To start 5 phase Signal through 15. 5. Is activated Trigger of 13. Help Activate 7.

Explanation / Answer

1. G1 and G1/S Cdk complexes

2. Cyclin production

3. Deploy Cdk inhibitors

5. MAP signalling cascade

6. Cyclin production

7. G1 and G1/S Cdk complexes

8. Retinoblastoma protein

9. Release from DNA

10. Cell proliferation genes

11. P53

12. P21 Gene

13. P21

14. Apoptosis

15. S Cdk

16. Actvates DNA replication

17. Prevents re-replication

18.Cdc 25

20. Wee1

21. Condensins

22. Chromosomes

23. Microtubule associated proteins

24. Microtubule destabilization

25. Securin

26. Separase

27. Cohesions

28. APC

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