ies tholt shows the cORaEC orden.in fror Prefrontal Cortex to the Nucleus Accumb
ID: 241074 • Letter: I
Question
ies tholt shows the cORaEC orden.in fror Prefrontal Cortex to the Nucleus Accumbens to the Ventral Tegmental Area with the Amygdala included. According to the Top-Down Theory of Brain Reward, select from the following group of neuroanatomic substrates that shows the CORRECT order. O8 Prefrontal Cortex to the Nucleus Accumbens to the Ventral Tegmental Area without the Amygdala included. C.Prefrontal Cortex to the striatum to the Ventral Tegmental Area with the Amygdala included. 13 Prefrontal Cortex to the striatum to the Ventral Tegmental Area without the Amygdala included.Explanation / Answer
1. Answer is option B
Prefrontal cortex to the nucleus accumbens to the ventral tegmental area with the amygdala. Major inputs to the nucleus accumbens include the prefrontal cortex, basolateral amygdala.
2. Answer is option D
The mesolimbic dopamine pathway is thought to play a primary role in thereward system. It connects the ventral tegmental area (VTA), one of the principal dopamine-producing areas in the brain, with the nucleus accumbens, an area found in the ventral striatum that is strongly associated withmotivation and reward. The ventral temporal area is located in mid brain, in occipital lobe
3. Answer is option B
A recent study on rats that used GABA agonists and antagonists indicated that GABAA receptors in the NAc shell have inhibitory control on turning behavior influenced by dopamine, and GABAB receptors have inhibitory control over turning behavior mediated by acetylcholine.
4. Answer is option A
Dopamine is synthesised from L-dopa. L-DOPA is converted into dopamine by the enzyme aromatic L-amino acid decarboxylase (also known as DOPA decarboxylase), with pyridoxal phosphate as the cofactor.
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