A mutation causing an addition or a deletion of one base pair resulted in the pr

Question

A mutation causing an addition or a deletion of one base pair resulted in the production of a nonfunctional mutant protein. The sequences of the normal and mutant proteins are given below Normal: Met Leu Ala Thr Gln Mutant: Met Leu Ala His Pro e Glu Ser Thr Was this mutation cause by an insertion or a deletion? Below, fill in the codons in the coding sequence of the mRNA that is translated into the mutant protein. If more than one codon is possible, just enter a single codon. NH2 Met Leu Ala His Pro le codons 5' AUG UUG

Explanation / Answer

Yes this is insertion of nucleotide the normal sequence code by the following sequence

Atgctggcgacccag and mutant having some insertion and code by the following sequence

Atgctggcgcatccgattgaaagcacc so there is some insetion after third amino acid which makes this protein nonfuctional.

The codon code for Met Leu Ala His Pro Ile glu Ser Thr will be Atg ctg gcg cat ccg att gaa agc acc

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