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A mutation causing an addition or a deletion of one base pair resulted in the pr

ID: 227281 • Letter: A

Question

A mutation causing an addition or a deletion of one base pair resulted in the production of a nonfunctional mutant protein. The sequences of the normal and mutant proteins are given below.

Normal: Met - Leu - Ala - Thr - Gln

Mutant: Met - Leu - Ala - His - Pro - Ile - Glu - Ser - Thr - .....

1) Was this mutation cause by an insertion or a deletion?

Below, fill in the codons in the coding sequence of the mRNA that is translated into the mutant protein. If more than one codon is possible, just enter a single codon.

   NH2    Met Leu Ala His Pro Ile codons 5' AUG    UUG    *codon*    *codon*    *codon*    *codon*

Explanation / Answer

Answer-

This mutation caused due to insertion.

The possible mRNA is

codon 5'- AUG- UUG- GCC- CAU- CCU- AUC-

for Glu (GAA)- His ( AGU)- Thr- (ACU)

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