The answer is 63%, I just don\'t know how to get there. Gene R codes for a prote
ID: 221402 • Letter: T
Question
The answer is 63%, I just don't know how to get there.
Gene R codes for a protein that completely inhibits the expression of gene H in the ABO blood group system. R^WT is the dominant wild-type functional allele, and r^ES is a recessive enhancer mutation that abolishes the expression of the R gene in red blood cells. A couple with genotypes |A| HH R^WT r^ES and |B| HH r^ESr^ES decide to have a child. Assume independent assortment among all three genes. What is the probability that the child will have blood type O? Enter a percentage rounded to a whole number (not decimal ratio) on the answer sheet.Explanation / Answer
In the following genotype HA encodes A blood gropu, HB encodes B, H encodes no antigen. Under RWT expression, the expression of H genes will suppress hence, result will always occur as O blood group.
HAH RWT rES x HBH rES rES
Gametes
HB rES
H rES
HA RWT
HAHB RWT rES [O]
HAH RWT rES [O]
HA rES
HA HB rES rES [AB]
HA H rES rES [A]
H RWT
HHB RWT rES [O]
HH RWT rES [O]
H rES
HHB rES rES [B]
HH rES rES [O]
Total ‘O’ blood group candidates are= 5 out of 8, which are 5/8 x100 = 62.5%
Gametes
HB rES
H rES
HA RWT
HAHB RWT rES [O]
HAH RWT rES [O]
HA rES
HA HB rES rES [AB]
HA H rES rES [A]
H RWT
HHB RWT rES [O]
HH RWT rES [O]
H rES
HHB rES rES [B]
HH rES rES [O]
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.