You have treated early Xenopus embryos with colchicine, a drug that causes the d
ID: 220349 • Letter: Y
Question
You have treated early Xenopus embryos with colchicine, a drug that causes the depolymerization of microtubules. a. Does this cause the embrvos to be dorsalized or ventralized? b. Briefly explain why the colchicine treated embryos would show this effect (dorsalized/ventralized), using the details that you know about Xenopus axis specification c. After removing the drug from the embryos, you want to perform an experiment to rescue axis specification in these treated embryos. You decide to inject mRNA into the embryos. What mRNA would you choose and briefly explain how it could be able to rescue axis specification.Explanation / Answer
a.
Colchicine is the drug that cause ventralized embryos.
b.
The rotation in the early xenopus embryo is inhibited by the drug called colchicines. The inhibition of microtubule formation leads to the ventralized of the embryo.
c.
Vg1 mRNA will be the choice to inject into the embryos. This is because it will help in the formation microtubules.
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