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MOLECULAR BIOLOGY Sarkosyl core histones Polyglutamate-+ o o o o O N o Primer ex

ID: 219504 • Letter: M

Question

MOLECULAR BIOLOGY

Sarkosyl core histones Polyglutamate-+ o o o o O N o Primer extension analysis of RNA Kr o Laybourn, P.J. and J.T. Kadonaga, Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II. Science 254 (11 Oct 1991) f. 2B, p. 239. Copyright O AAAS. View figure 13.12. ) Which method was used to measure gene transcription? ) The multiple bands indicate more than one transcriptional start site. Why is there more than one transcriptional start site ) What do the results indicate about the function of core histones?

Explanation / Answer

1. Western blot is the method use to measure gene transcription.

Core histone function indicate that Histones act as spools around which DNA winds and helps in gene regulation