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iscms/mod/ibis/view.php?id-4711419 Jump to... uestion 15 of 15 Map do Genetics:

ID: 217948 • Letter: I

Question

iscms/mod/ibis/view.php?id-4711419 Jump to... uestion 15 of 15 Map do Genetics: A Conceptual Approach 6th Edtion MHE/Freeman Using breeding techniques, Andrei Dyban and V.S. Baranov created mice that were trisomic for each of the different mouse chromosomes (Cytogenetics of Mammalian Embryonic Development. Oxford: Oxford University Press,Clarendon Press; New York: Oxford University Press, 1987) They found that only mice with trisomy 19 developed fully. Mice trisomic for all other chromosomes died during development 2.5 2.0 1.5 1.0 0.5 0. 12 13 14 15 16 17 1 For some of these trisomics, they compared the length of development, before the embryo died, as a function of the size of the chromosome that was present in three copies This data is presented in the R. Williams, and A Amon. Fig 2B.) Chr 13 Chr 14 Chr 12 Chr 10 on the left (E. Torres, B Genetics 179:737-746, Chr 16 Chr 18 Choose the statements that best describe the findings based on the graph presented Length of embryonc Sevelopment idays) There is a positive correlation between size of the trisomic chromosome and the length of embryonic development Mice trisomic at small chromosomes survived longer than mice trisomic at larger chromosomes There is an inverse relationship between size of the trisomic chromosome and the length cf embryonic development. The longer the mice developed, the larger their chromosomes became. Continued below Previous 2 Check Answer Next Ex

Explanation / Answer

Statements that best describe findings from the graph:-

1.Mice trisomic at smaller chromosomes survived longer than mice trisomic at larger chromosomes.
2.There is an inverse relationship between size of trisomic chromosome and length of embryonic development.

Best possible explanations for these results:-

1.Being trisomic for larger chromosomes affects the dosage of more genes and is more detrimental causing development to cease at an early stage.