Questions to Accompany Guide Sheet 2 SOD1 1. What organism is the superoxide dis
ID: 216902 • Letter: Q
Question
Questions to Accompany Guide Sheet 2 SOD1 1. What organism is the superoxide dismutase 1 from in the 1B4L crystal structure? Write the first author and title for the primary citation for this crystal structure. 2. I structure? Explain what "resolution? meansfor a crystal structure. Carefully examine the secondary structure in the crystal structure and record any positions where the PSIPRED predictions were incorrect. 4. 5, PSIPRED states its predictions are-80% correct. Do you agree this is a good estimate of the accuracy?Explanation / Answer
Answer:
1) What organism in the superoxide dismutase 1 from in the 1B4L crystal structure?
2) Write the first author and title for the primary citation for this crystal structure
3) What is the resolution for this crystal structure? Explain what "resolution" means for a crystal structure.
4) Carefully examine the secondary structure in the crystal structure and record any positions where the PSIPRED predictions were incorrect.
PSIPRED structure prediction takes 1hr to 24hrs, will update this part once the report is generated.
5) PSIPRED states its predictions are ~80% correct. Do you agree this is a good estimate of the accuracy?
PSIPRED secondary structure predictions are derived using neural network machine learning algorithms. It predicts location of alpha helices and beta strands with approximately 80% accuracy which is a good estimate considering the complexity in determining protein secondary structure using predictive methods.
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