2. Describe the roles in synaptic transmission of the following: calcium, precur

Question

2. Describe the roles in synaptic transmission of the following: calcium, precursors, synthesizing enzymes and degrading enzymes. 3. What do autoreceptors and retrograde transmitters have in common? . What do reuptake and degrading enzymes have in common? 5. Briefly, define agonist and antagonist. 6. How would an agonist affect each step of synaptic transmission? A)manufacture b)release c)bind d)deactivate 7. How would an antagonist affect each step of synaptic transmission? A)manufacture b)release c)bind d)deactivate 8. What is the difference between an ionotropic receptor and a metabotropic receptor? 9. How did Loewi prove that neural communication could be based on chemical rather than electrical signals? 10. Which neurotransmitters are "monoamines," and how are they related to each other? 11. For each neurotransmitter, describe the major function and important agonists or antagonists a)Acetylcholine, b)dopamine, c)norepinepherine, d)epinephrine, e)serotonin, f)GABA, g)glutamate h)glycine, i)opioid peptides (e.g. endorphins), jjnitric oxide. 12. How to do neuropeptides differ from other neurotransmitters? 13. How do neurotransmitter gases differ from other neurotransmitters? 4. What are receptor subtypes? What is their significance for drug development? 5. Explain the importance of the therapeutic index in a dose-response curve (DRC) 16. How does marijuana affect synaptic mechanisms and behavior? 17. Which drugs are classified as hallucinogens, and what neurotransmitter system do most of them 18. Describe the four different perspectives on drug abuse 9. Explain the relationship between addiction and the nucleus accumbens. 20. Describe the details from Figure 4.7: Drug effects on presynaptic mechanism, and Figure 4.8 Drug effects on postsynaptic mechanisms. 21. Describe how these drugs affect neurons: reserpine, textrodotoxin, amphetamines, caffeine, cocaine 22. Describe the major effect on synaptic mechanisms (i.e. agonist or antagonist? Which step in synaptic activity?) and effect on behavior of these drugs: a)antischizophrenics/antipsychotics, (e.g. chlorpromazine/Thorazine), b)antidepressants (MAO inihibitors, tricyclics, selective serotonin reuptake inihibitors), cjanxiolytics/antianxiety drugs: (e.g. benzodiazepines), d)opiates (morphine, heroin). 23. (Honors Section Only: Questions on Cannabidiol Worksheet)

Explanation / Answer

Q5) Agonist:- As far as the agonist is concerned it is mostly a drug, that ties a receptor molecule and starts a response like that of another molecule, generally a neurotransmitter, starts the normal effects of the transmitter on that receptor

Antagonist:- As far as the antagonist is concerned its also a drug, that prevents the action of a transmitter, ligand that ties to a receptor and does not activate it, by that blocking it from being activated by other ligands.

Q12) As far as the neuropeptides are concerned these are one type of neurotransmitters, and are composed only of peptides i.e, proteins and having larger molecular weights. Similarly as far as the neurotransmitters are concerned, these are different types of low molecular weight molecules which includes amino acids and and small peptides. Hence, this is how neuropeptides differ from neurotransmitters.

Related Questions

Navigate

• Browse (All)
• Browse 2
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.