1) Dogs with short legs have a form of achondroplasia. A) (2 points) From the pe
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1) Dogs with short legs have a form of achondroplasia. A) (2 points) From the perspective of the molecular basis. Give one similarity and one difference when comparing this to human achondroplasia. B) (2 points) Will a kinase inhibitor be an effective drug for both dogs and humans? Explain your reasoning C) (2 points) What is one criteria for a kinase inhibitor with respect to it being a safer drug? D) (3 points) Kinase inhibitors are also useful for treating HER2 positive forms of breast cancer. But the tumors can become resistant to these drugs. Explain the molecular basis for this resistance E) (3 points) Once a HER2 cancer line becomes resistant, are there other drugs that could be employed that could still be effective? Explain your reasoning.Explanation / Answer
The genetic basis for both the species for the disease is different but the pathophysiology that develops is same
No. Since the causes are different
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