27. At the biochemical level, why does a carnitine deficiency lead to increased

Question

27. At the biochemical level, why does a carnitine deficiency lead to increased fat deposition in the liver? A. In the absence of carnitine, the liver stores large amounts of glycogen, which is converted into fatty acids and stored as TAGs within the liver. B. Carnitine is an activator of hepatocellular TAG lipases; as a result, in the absence of carnitine, lipase activity is turned off, favoring TAG synthesis. C. Because -oxidation is blocked, fatty acids arriving to the liver from the blood cannot be oxidized and are instead stored in intracellular lipid droplets. D. Carnitine is an inhibitor of fatty acid synthesis; as a result, in the absence of carnitine, fatty acid synthesis is stimulated, leading to an increase in stored TAGs in the liver.

Explanation / Answer

The question asked is given along with the answer.The reasons why carnitine defiency leads to fat deposition in liver is given by the student itself in the points A,B,C,D.

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