Please answer EVERY QUESTION Problem Set Questions: 1) Provide a reason explaini

Question

Please answer EVERY QUESTION
Problem Set Questions: 1) Provide a reason explaining why the formation of secondary structure is not the main driving force for protein folding. 2) The ridges and grooves of an -helix form an angle of ~25° or ~45° to the helical axis. What are the spacings between the residues that line these two types of grooves? How do these geometric considerations constrain the packing of pairs of helices at relative angles of 50° and 20°? 3) Heptad repeats define coiled coils, which are a type of supersecondary structure where two -helices are wrapped around each other. Given that - helices have 3.6 residues per turn, how can a heptad repeat (i.e. 7 residues) define a coiled coil of a-helices. 4) How do helix dipoles stabilize the structure of a four helix bundle?

Explanation / Answer

1) this is because the formation a secondary structure, a correct secondary structure would take a long time to form according to levinthal paradox.

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