A sample problem - A highly virulent strain of a common and previously innocuous

Question

A sample problem - A highly virulent strain of a common and previously innocuous virus has been discovered and you have decided to conduct a series of experiments to understand what has caused this new strain of virus to be so virulent. Fortunately, the innocuous strain was known to have a small, linear double-stranded DNA genome with nfnes Wehat the ilent srain has two new geñes Innocuous strain: Virulent strain: geneA geneB geneC geneA geneB geneC geneD gene Design an experiment to test if geneD is necessary for the virulence of this type of virus.

Explanation / Answer

The gene D can be isolated and introduced into a nonvirulent gene. This can help to identify whether the gene D is responsible for virulence. To know this, transformed nonvirulent virues with gene D is infected into a mouse or any other laboratory animal. if the transformed nonvirulent virus able to cause disease in the animal, then it can be known that gene D is responsible for virulence and introduction of gene D into nonvirulent virus transformed it into virulent strain.

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