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PLEASE HELP ME ANSWER ALL THE QUESTIONS AND GIVE EXPLANATION Starting with a pop

ID: 182642 • Letter: P

Question

PLEASE HELP ME ANSWER ALL THE QUESTIONS AND GIVE EXPLANATION

Starting with a population of genetically identical mice, you discover two new independent mutant strains in which animals have epileptic seizures. You do some experiments and find out that in both strains the epileptic seizures are caused by single-gene mutations. You cross a mutant mouse from one strain with a mutant mouse from another strain and find that none of their many offspring undergo spontaneous seizures. From this experiment you would conclude that the two mutant strains of mice most likely contain mutations in (Briefly explain your answer):

a) The same DNA base pair position in a particular gene

b) The same gene, but not necessarily the same base pair position

c) Two different genes

Explanation / Answer

Answer:

From this experiment you would conclude that the two mutant strains of mice most likely contain mutations in

a) The same DNA base pair position in a particular gene

b) The same gene, but not necessarily the same base pair position

c) Two different genes - Correct Option (Since none of the offsprings produced after mating the mice undergoes spontaneous seizures, therefore the two strains have mutations in different genes that are responsible for spontaneous seizures. Since, in this case spontaneous seizures appears to have a autosomal recessive pattern, both copies of the gene in each cell have mutations.

Therefore the absence of spontaneous seizures in progency can be attributed to mutations in two different genes in the two mutant strains of mice.)

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